Robin G. Lorenz, MD, PhD – Member Spotlight

Robin G. Lorenz, MD, PhD
Senior Director, Department of Pathology
Genentech, Inc., South San Francisco, CA, USA

Dr. Robin Lorenz is a long-time member of the American Society for Investigative Pathology and has recently served in leadership. She was an At-Large Member of the ASIP Council from 2016-2019, and is currently the ASIP Representative to the Training and Career Opportunities Subcommittee of FASEB Science Policy Committee, as well as a current member of the ASIP Meritorious Awards Committee. Dr. Lorenz served as Senior Assistant Editor for The American Journal of Pathology from 2013-2017, and is a current member of the Editorial Board. In 2016, Dr. Lorenz received the ASIP Robbins Distinguished Educator Award.

Dr. Lorenz received her BS in Biology from Stanford University in 1984 and then attended Washington University in St Louis as a Medical Scientist Training Program fellow, where she earned an MD and a PhD in Immunology in 1990. She completed residency training in laboratory medicine (clinical pathology) at Barnes-Jewish Hospital, and then transitioned to Assistant Professor in the Departments of Pathology and Medicine at Washington University in 1994. In addition to directing a basic science research lab focused on chronic inflammation in the gastrointestinal tract, Dr. Lorenz served as Co-Director of the Joint Clinical Immunology Laboratory of Barnes-Jewish Hospital and St Louis Children’s Hospital and Associate Director of the Laboratory Medicine Residency Training Program. Dr. Lorenz joined the Department of Pathology at the University of Alabama at Birmingham (UAB) in 2002 as an Associate Professor, and was promoted to Professor in 2007. Dr. Lorenz’s laboratory at UAB focused on gastrointestinal immune responses to both pathogenic (H. pylori) and commensal microbiota and the impact of these responses on systemic autoimmune diseases and was funded by the National Institutes of Health (NIH), the Juvenile Diabetes Foundation, and the Crohn’s and Colitis Foundation. Dr. Lorenz played many key roles at UAB, including serving as Associate Dean for Physician Scientist Development, Director of the UAB Medical Scientist (MD-PhD) Training Program, and Director of the UAB Medical Student Summer Research Program. At UAB, Dr. Lorenz held secondary faculty appointments in the UAB departments of Medical Education and Microbiology, and was a member of the Comprehensive Cancer Center, the Comprehensive Diabetes Center, and the Comprehensive Arthritis, MSK, Bone & Autoimmunity Center. While working at UAB, Dr. Lorenz earned an MS in Healthcare Quality and Safety (2017). Dr. Lorenz has a longstanding involvement in the Academy of Clinical and Laboratory Physicians and Scientists (ACLPS), where she participated in the formulation of a national curriculum for the teaching of clinical immunology. More recently, she was one of the leaders in the national dialogue on whether Pathology should form a research track for Pathology residents. This track was recently endorsed by the American Board of Pathology and is now available to Pathology residents who are training to become physician-scientists.

Dr. Lorenz assumed her new position of Senior Director of Research Pathology at Genentech in South San Francisco, CA in 2018. At Genentech, her department provides high quality pathology support to laboratory and clinical scientists engaged in biomarker strategy/development/deployment across the drug development pipeline. These activities extend into “late stage” clinical development efforts (Phase III clinical trials). The Research Pathology department provides Research and Development personnel with intellectual and technical expertise concerning pathology-related study design, tissue selection, microscopic interpretation, analytical techniques, and support for regulatory and clinical queries. The Pathologists’ collaborative support of research and development scientists include histopathology interpretive expertise informed by traditional diagnostic categories and by detailed and current understanding of molecular and cellular biology. These activities provide cutting edge technology platforms for analysis of fresh, frozen and formalin-fixed paraffin embedded tissues and cell lines used to assess (i) new therapeutic targets and pathways and (ii) biomarkers relevant to diagnosing and treating human disease. The Department also manages 6 core pathology laboratories that include necropsy, clinical pathology, histopathology, immunohistochemistry and in situ hybridization, a human tissue biorepository, and advanced light microscopy, electron microscopy and digital pathology.