HCS and ASIP member Dr. Alejandro Adam recently co-authored two preprints with collaborators at Albany Medical College, the University of Wisconsin, Madison and the Morgridge Institute for Research. This research, led by Drs. Ariel Jaitovich (Albany Med) and Joshua Coon (UW-Madison), shows how multiplexed measurements, large-scale multi-omics analysis and artificial intelligence can shed light into why some patients quickly recover, while others have a much worse prognosis. The data shows high levels of CCL19, but low levels of PDGF-AA, dysregulation of platelet function, blood coagulation, acute phase response, and endotheliopathy in patients with worse prognosis, providing insight into novel potential therapeutic interventions. All cytokine profiling, metabolomics, lipidomics, proteomics, transcriptomics from a prospective cohort of 120 patients were made freely available to the whole scientific community.
- #PISA2020 Day 5Program Yesterday was another full day of science, mentoring, and networking at PISA 2020. With Day 4 of the meeting in the books, we find ourselves at Day 5 – the final day of PISA 2020. TODAY at PISA 2020, we begin with Trainee Advising Sessions at 8:00 AM and 9:00 AM on the topics […]
- Pathologists Fighting COVID-19 – Sally DavisK-State Assistant Professor of Experimental Pathology, Dr. A. Sally Davis, an ASIP member and HCS Councilor, will lead USDA-National Institute of Food and Agriculture Rapid Response project “Translating SARS-CoV-2 Research Into Practical Solutions For The Meat And Poultry Processing Industry” to find scientific solutions to protect meat and poultry plant workers and their surrounding communities […]
- Mouse Models Reveal Role of T-Cytotoxic and T-Reg Cells in Immune Response to Influenza: Implications for Vaccine DesignArticle of Interest: Abstract: Immunopathologic examination of the lungs of mouse models of experimental influenza virus infection provides new insights into the immune response in this disease. First, there is rapidly developing perivascular and peribronchial infiltration of the lung with T-cells. This is followed by invasion of T-cells into the bronchiolar epithelium, and separation of […]