Dr. Piyali Dasgupta

Dr. Piyali Dasgupta is an Associate Professor at the Department of Biomedical Sciences, Joan C Edwards School of Medicine, Marshall University.  Originally from India, Dr. Dasgupta came to the United States to pursue her postdoctoral studies at Columbia University, New York and the Moffitt Cancer Center, Tampa, Florida.  Research in Dr. Dasgupta’s laboratory examines the anti-cancer activity of capsaicin (the spicy ingredient of chili peppers) in human small cell lung cancer (SCLC). Data from her laboratory show that capsaicin robustly suppresses the growth and metastasis of human SCLC.  In addition, she observed that capsaicin sensitized human SCLC cells to the apoptotic activity of camptothecin.  Current research in her laboratory involves studying the anti-tumor activity of non-pungent capsaicin-like compounds (isolated from other varieties of chili peppers).  Dr. Dasgupta was the only junior scientist nationwide to be selected for the prestigious ASPET-Astellas award in translational pharmacology in 2009. Marshall University has honored her with several awards like the Marshall University Distinguished Artists and Scholars Award (2009), John and Francis Rucker Graduate Faculty Mentoring Award (2012) and the Dean’s Award for Excellence in Basic Research (2013). Her research has been funded by multiple funding agencies like National Cancer Institute (NCI), American Society of Pharmacology and Experimental Therapeutics (ASPET), Pharmaceutical Manufacturer’s Association (PhRMA) and Flight Attendant Medical Association (FAMRI).

INVOLVEMENT IN ASIP

Dr. Piyali Dasgupta is the co-chair of the Tumor Microenvironment and Metastasis (TMM) scientific interest group (SIG) of the American Society of Investigative Pathology (ASIP). She contributes to the ASIP newsletter and the TMM social media website.  She is enthusiastic about mentoring undergraduates and women scientists in biomedical sciences. 

WEBSITE

Dasgupta

The ability of cancer to travel through the blood (or lymph) to colonize distant organs and form secondary tumors is termed as METASTASIS. The pro-metastatic ability of primary tumors is the reason why cancer is a lethal disease. A vital step of the metastatic cascade is the invasion of cancer cells into the basement membrane and in to blood vessels.

Capsaicin analog could help treatment-resistant lung cancer

A new study found that non-pungent synthetic analog of capsaicin — the compound that makes chili peppers hot — made small cell lung cancer cells more responsive to treatment. Small cell lung cancer is a very aggressive form of cancer with a low survival rate.

Marshall faculty awarded $750,000 grant to continue program to diversify science and engineering faculty – Marshall University Research Corporation

Wednesday, August 26, 2009 HUNTINGTON, W.Va. – A group of faculty members at Marshall University has been awarded $750,000 by the National Science Foundation (NSF) to continue a successful initiative to increase the number of female science, technology, engineering and mathematics (STEM) faculty members at the university. Dr. Marcia A.

Study focuses on potential lung cancer therapies – Marshall University Research Corporation

Wednesday, March 13, 2013 [social_share/] HUNTINGTON, W.Va. – Scientists from Marshall University, along with colleagues at Alderson-Broaddus College in Philippi, have completed a study that may eventually help lead to the development of new treatments for lung cancer. Their results were published in

ASIP 2019 Annual Meeting at Experimental Biology #ASIP2019 at #ExpBio