Frank W. Fitch, MD, PhD | 1929-2021

Frank W. Fitch (1929–2021) was professor emeritus of the Department of Pathology and former director of the Ben May Institute (currently the Ben May Department of Cancer Research) at the University of Chicago. Dr. Fitch was an AAI past-president, EIC, FASEB president, and an ASIP Lifetime Emeritus member. Dr. Fitch was president of The American Association of Immunologists from 1992 to 1993 and served on the AAI Council from 1987 to 1994. He also served as editor-in-chief of The Journal of Immunology from 1997 to 2002. From 1993 to 1994, Dr. Fitch was president of the Federation of American Societies for Experimental Biology. He was awarded the AAI Excellence in Mentoring Award in 2004, the AAI Distinguished Service Award in 2002, and the AAI Lifetime Achievement Award in 1996. Dr. Fitch was elected a Distinguished Fellow of AAI in 2019.

Dr. Fitch had a number of significant accomplishments during his 40 years as a faculty member at the University of Chicago School of Medicine. His research in Immunology lead to innovations in the treatment of Rh disease in mothers with Rh incompatibility, techniques for T-cell cloning used in multiple research laboratories around the world and the advancements in monoclonal antibody techniques that are now used as the standard for immunotherapy treatment of multiple cancers including breast cancer. While at the University of Chicago, he trained 35 PhD students and seven post-doctoral fellows. 

He was the president of the Federation of American Societies for Experimental Biology (FASEB) and the recipient of the Norman McLean faculty award from the University of Chicago. He was a John Simon Guggenheim fellow a Borden research award recipient and a Lederle medical faculty award recipient. Many of his PhD students went on to accomplished academic careers leading multiple academic departments around the world. 

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In Memorium – Thomas Scott Edgington, MD 1932 -2021

Thomas Scott Edgington was born on February 10, 1932 and passed away on January 22, 2021. He served as chairman of the Department of Pathology at Scripps Clinic while also directing his basic research laboratory at the Scripps Research Institute. He formed a vascular-biology unit, drawing members from several Scripps’ departments who, collectively, generated a mountain of highly original and fundamentally important observations over the years. Edgington loved life and lived it well. He will live long in the minds and hearts of his family, his many friends and colleagues, and the more than 70 postdoctoral fellows he trained.

Dr. Edgington served as President of the ASIP in 1989-1990, and was the 1995 recipient of the ASIP Rous-Whipple Award.

Thomas Scott Edgington – Polymath, Colleague, Mentor, Friend from Scripps Research

Thomas Scott Edgington – Polymath, Colleague, Mentor, Friend

March 02, 2021 Written by Francis V. Chisari, MD and Michael B.A. Oldstone, MD Thomas Edgington, an outstanding scientist and a world leader in the field of vascular biology, passed away Jan. 22, 2021, just 19 days before his 89 th birthday.


Thomas Edgington Obituary – San Diego, CA

Celebrate the life of Thomas Edgington, leave a kind word or memory and get funeral service information care of El Camino Memorial – Sorrento Valley.

In Memorium: Dr. Emanuel Rubin

Dr. Emanuel Rubin

Emanuel Rubin, an internationally recognized pathologist and leading innovator in education, died on February 13, 2021. Born in Brooklyn in 1928 and raised in Atlantic City, Dr. Rubin launched his exceptional academic career at Harvard Medical School (MD, 1954) after earning a BS degree from Villanova in 1950. He served in the Navy from 1955 to 1957, and he entered the field of pathology as a trainee in the Mt, Sinai pathology residency program from 1958 to 1962. Dr. Rubin joined the faculty of the Department of Pathology, Mt. Sinai School of Medicine in 1962 and had a rapid academic ascension to the rank of professor in 1968, and subsequently, as Chair of the Department in 1972. Dr. Rubin moved to Philadelphia in 1977 as Chair of the Department of Pathology at the then Hahnemann Medical School combined with the Medical College of Pennsylvania (later Drexel University Medical School). He moved to become Chair of the Department of Pathology at Jefferson Medical College (currently Sidney Kimmel Medical College) of Thomas Jefferson University in 1986, in part motivated by the Dean’s efforts to enhance pathology education for medical students. In 1987 he received the status of Adjunct Professor of Biochemistry and Biophysics from the University of Pennsylvania School of Medicine. Dr. Rubin made seminal contributions to our understanding of liver function, both normal and abnormal. At a time when alcohol-induced liver injury was considered to be the result of nutritional deficiencies (so called “nutritional cirrhosis”), Dr. Rubin’s experiments in non-human primates and human volunteers changed the paradigm to demonstrate the hepatotoxicity of excessive alcohol consumption that was independent of nutritional status. He subsequently collaborated with scientists at the University of Barcelona to demonstrate that the cardiomyopathy resulting from alcohol toxicity was proportional to the cumulative dose of alcohol, and that liver and cardiac damage occurred synchronously. These seminal findings laid the foundation for Dr. Rubin to establish a well-funded alcohol research center at Jefferson.  Another highlight of Dr. Rubin’s career, following his arrival at Jefferson, is his rich legacy of educational contributions to the field of pathology. First and foremost is the Rubin’s Pathology textbook, the first edition launched in 1988 and now in its eighth edition. It is a global resource and has been translated into multiple languages, including Spanish, Portuguese, Italian, and Japanese. Dr. Rubin is survived by his wife, Dr. Linda Haegele, five of his six children: Daniel, a pathologist; Jonathan, a radiologist; Rebecca, a lawyer; Ariel, a musician; and Ethan, a graduate student. Tragically, his oldest son, Raphael, also a pathologist and a member of our faculty, passed away in September, 2011. Dr. Rubin is also survived by multiple grandchildren and great-grandchildren.

Dr. Rubin’s awards include

  • American Medical Writer’s Award for Best Medical Textbook of the Year, 1989
  • Doctor Honoris Causa, University of Barcelona, Spain, 1994
  • The F.K. Mostofi Distinguished Service Award of U.S.-Canadian Academy of Pathology, 1996
  • National Institutes of Health (NIH) MERIT Award, Bethesda, MD, 1996-2006
  • Tom Kent Award for Excellence in Pathology Education, Group for Research in Pathology Education (GRIPE), 2001
  • Doctor Honoris Causa, Republic of Italy, 2003
  • Lifetime Scientific Achievement Award, Sbarro Health Research Organization, 2004
  • Distinguished Service Award, Association of Pathology Chairs, 2006
  • Gold Medal Award, International Academy of Pathology, 2006
  • Gold-headed Cane Award (research), American Society for Investigative Pathology, 2008
  • Lifetime Achievement Award, Research Society on Alcoholism, 2015
  • Robbins Distinguished Educator Award, American Society for Investigative Pathology, 2018
  • Honorary Distinguished Member of Faculty Award, The Hebrew University of Jerusalem

In Memoriam: Samuel W. French, MD


We were saddened to learn that long-time ASIP member Dr. Samuel W. French passed away on Christmas day at home in Rancho Palos Verdes, CA. Dr. French was 94 years old. As many of you know, he was an exceptional pathologist, educator and researcher with tireless and insatiable academic passion for more than half a century. His prolific and original research particularly on alcoholic liver disease (ALD), resulted in nearly 500 publications. His seminal contributions to science on hypoxia, nutrition, and Mallory-Denk bodies in ALD, were recognized by highest honors including Lifetime Achievement Award by Research Society on Alcoholism and the 2014 ASIP Gold Headed Cane Award. Dr. French was an active ASIP member from January 1, 1965 until his death.

He graduated from UC Berkley and UC San Francisco Medical School and trained in UCSF General Hospital and New England Deaconess Hospital in Boston. He was Vice Chairman of Pathology at UC Davis (1978-82), Chairman of Pathology at University of Ottawa (1982-1990), Chief of Anatomic Pathology at Harbor-UCLA Medical Center (1990-) and Distinguished Professor of Pathology at UCLA (2004-). He was one of the original 4 principal investigators for NIAAA/NIH-supported Southern California Research Center for ALPD and Cirrhosis founded in 1999 and served as director of the center’s Morphology Core, providing his unmatched pathologic expertise and wisdom to numerous projects pursued by the center members and investigators across the nation and around the world. Many of us are beneficiaries of his professionalism and friendship to which we are deeply indebted. It is a huge and sad loss and he will be missed. We offer sincere condolences and prayers to Barbara, his wife, and his family members. A virtual memorial service is planned in the future. For more information, please contact Ms. Adriana Flores of Harbor-UCLA Medical Center.

Isaiah “Josh” Fidler, DVM, PhD – 1936 – 2020

Isaiah “Josh” Fidler, DVM, PhD

Isaiah “Josh” Fidler, DVM, PhD, passed away on May 8, 2020, at his home in Houston, TX, following a long illness. Dr. Fidler was a long-time faculty member at the M.D. Anderson Cancer Center in Houston and was a long-time member of the American Society for Investigative Pathology (ASIP). His research program was exceptional and he received numerous awards during his career, including the ASIP Gold-Headed Cane Award in 2016.

Isaiah Fidler Obituary – Houston, TX | Houston Chronicle

Isaiah “Josh” Fidler, D.V.M., Ph.D., 1936-2020Isaiah “Josh” Fidler, D.V.M., Ph.D., passed away on May 8, 2020, at his home in Houston following a long illness.Dr. Fidler was born in Jerusalem on Dec. 4, 1936 to Shoshana Stern and Pinchas Fidler. His father, a world renown soccer player, died in Israel’s war of independence in 1948.

He took on the mystery of metastasis. Now he’s taking on brain cancer.

From his days as the head of Metastasis Biology at the National Cancer Institute, to his current work at MD Anderson exploring new therapeutic approaches to challenging diseases such as brain cancer, his name has been heavily imprinted on the timeline of “firsts” in the quest to understand how cancer spreads.